GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs11723261 | 1 | rs4129956 | chr4:302008 | ZNF718 | chr4:53272-156488:+ | 0.67 | 7.27 | 1.03E-10 | Immune response to smallpox vaccine (IL-6) |
| THYM | cis | rs9457247 | 1 | rs413232 | chr6:167400972 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs2275426 | 1 | rs4134386 | chr1:46395089 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs9362426 | 1 | rs414013 | chr6:88085866 | C6orf164 | chr6:88032306-88109459:+ | -0.5 | -4.99 | 2.68E-6 | Depressive episodes in bipolar disorder |
| THYM | cis | rs2243480 | 1 | rs4145008 | chr7:65647511 | CCT6P1 | chr7:65216092-65228661:+ | -0.67 | -5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs1401999 | 1 | rs4148571 | chr3:183720576 | ABCC5 | chr3:183637726-183735727:- | 0.5 | 4.38 | 3.08E-5 | Anterior chamber depth |
| THYM | cis | rs1401999 | 1 | rs4148575 | chr3:183702275 | ABCC5 | chr3:183637726-183735727:- | 0.48 | 4.28 | 4.53E-5 | Anterior chamber depth |
| THYM | cis | rs2243480 | 1 | rs4149468 | chr7:65825690 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs9457247 | 1 | rs415842 | chr6:167406681 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs415890 | chr6:167406633 | RNASET2 | chr6:167343008-167412795:- | 0.47 | 7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs416131 | chr6:167406544 | RNASET2 | chr6:167343008-167412795:- | 0.47 | 7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs2243480 | 1 | rs419603 | chr7:65597341 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.31 | 7.1E-7 | Diabetic kidney disease |
| THYM | cis | rs9457247 | 1 | rs421214 | chr6:167396629 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.91 | 4.62E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs422094 | chr6:167397033 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs2243480 | 1 | rs422164 | chr7:65586605 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.31 | 7.1E-7 | Diabetic kidney disease |